Hayato Gokudera (獄寺 隼人 Gokudera Hayato) is a 14-year-old transfer student from Italy who was placed in Tsuna's class. Gokudera is a dynamite expert nicknamed "Smokin' Bomb Hayato" (スモーキン・ボム 隼人 Sumōkin Bomu Hayato), or "Hurricane Bomb Hayato" in the anime. He keeps various explosives hidden on his body and uses those explosives liberally by lighting them with a cigarette (or several) held in his mouth. Initially, he comes to Japan in order to test Tsuna's strength, and after the latter risks his life to save Gokudera, he devotes himself entirely to Tsuna, having sworn to become his right-hand man. A hot-headed and short-tempered youth, he continuously gets into fights with several of the other characters, especially to those who try to get too close to Tsuna. Despite his personality, he is considered to be a genius, excelling in his academic studies.He is voiced by Hidekazu Ichinose in the anime.
Takeshi Yamamoto (山本 武 Yamamoto Takeshi) is the 14-year-old popular baseball star of Namimori Middle School. Despite his carefree and outgoing personality, he initially has no confidence in doing anything other than baseball, even attempting to commit suicide after sustaining major injury to his arm. After Tsuna reassures him, the two become close friends, and Reborn tries to recruit him into the Vongola Family.He hardly takes anything seriously, and is usually oblivious to what is truly happening around him, often tricked by Reborn into participating in Mafia-related events because he thinks that they are all just playing a game.Though he becomes a dedicated and valuable member of Tsuna's family, growing to become a fighter who excels at swordsmanship, he still does not understand the full extent of the situation surrounding the Mafia.He is voiced by Suguru Inoue in the anime.
Lambo (ランボ Ranbo) is a cow suit-clad 5-year-old assassin from Italy affiliated with the Bovino ("Bovino" means "bovine" in Italian) Familia. He has a huge afro (which he stores a variety of objects in, such as snacks and weapons) with horns on the sides of his head. Despite being a hitman, he lacks the emotional maturity and discipline that Reborn has and is also very conceited as well as being a crybaby. In order to prove that he is worthy of becoming his own family's boss, he comes to Japan to kill Reborn, though he only proves that he is no match for the Vongola hitman. His main choice of weapons are hand grenades, and his future dream is to rule the world. He also possesses his family's Ten-Year Bazooka, which replaces his present self with another version of himself ten years into the future. The 15-year-old Lambo remains a crybaby, though his good looks make him more charming to others.His child self is voiced by Junko Takeuchi, while his older self is voiced by Kenjirō Tsuda in the anime.
Ryohei Sasagawa (笹川 了平 Sasagawa Ryōhei) is the 15-year-old passionate member of the boxing club at Namimori Middle School. He constantly asks others he believe are strong to join his club, most notably Tsuna. In response, Reborn wants to recruit him into Tsuna's family.Every time he sees Tsuna and his family doing something strange, he gets fired up and always wants to be a part of it. Because of his energetic character, however, he does not understand the full extent of Tsuna's connection with the Mafia, but still does everything that he can to protect him and fights with as much spirit and confidence as the others. Proficient in hand-to-hand combat, his boxing training lead to his peak physical condition. He has a habit of always saying "to the extreme" as a single response or as an ending to his sentences. He is voiced by Hidenobu Kiuchi in the anime.
Kyoya Hibari (雲雀 恭弥 Hibari Kyōya) is the leader of Namimori's Discipline Committee, or Prefects, whose members happen to be a group of delinquents loyal to him despite his lack of care for them. Though he mostly speaks in a calm tone, Hibari is an excellent but violent fighter himself, who uses a pair of tonfa as his primary weapons. Though he uses his status to harass others, he actually has great pride in his school and has a soft side toward animals and small children. However, students are not the only ones who fear him, teachers and other town residents know of him as well since he enforces his form of order throughout the entire town. He prefers to be alone, usually beating up those who crowd near him. Despite caring little about the events surrounding Tsuna and his friends, Hibari takes a great interest in Reborn after seeing his abilities, which is reciprocated by Reborn, who wants to recruit him as part of Tsuna's own family.He is voiced by Takashi Kondo in the anime.
Mukuro Rokudo (六道 骸 Rokudō Mukuro ) is a 15-year-old Mafia criminal who escaped from an Italian prison, which held some of the most dangerous Mafia criminals, before he was to be executed. Not long after, he, along with his two subordinates, came to Japan, enrolled in Kokuyo Junior High, and started the Kokuyo Gang, which consists of heinous criminals whom have recently escaped from prison.Skilled in casting illusions as well as mind control, He attempts to take his revenge on the Mafia by taking over Tsuna's body and using him to wreak havoc. When his plan fails due to Tsuna's interference, he is once again imprisoned. However, later on in the series, after possessing the body of Chrome Dokuro, he takes on a more supportive role for the series' main characters, though still prefers not to associate with them.He is voiced by Toshinobu Iida in the anime.
Chrome Dokuro (クローム 髑髏 Kurōmu Dokuro), originally named Nagi (凪), is a 13-year-old Japanese girl who wears a Kokuyo school uniform. Mukuro Rokudo uses her as a vessel after he saved her life by creating illusionary organs for her when she lost her right eye and some of her organs in an accident. Chrome has been shown using two of Mukuro's six skills: creating illusions and summoning beasts that kill the enemy.The Japanese rōmaji of her name, Kurōmu Dokuro, is an anagram of Mukuro Rokudō.
Chrome is the named holder of the Mist Ring, and thus battles Mammon in the Vongola Tournament. When she is overwhelmed by Mammon's powers, Mukuro takes control and defeats him.After being transferred into the future, her physical condition takes a turn for the worse as several of her internal organs begin to fail. However, under Adult Hibari's instructions, she uses the power of her Vongola Ring to sustain her organs via her own illusions, thus avoiding any immediate danger. Afterwards she is given the Mist Vongola Box Weapon, the Demon Spade Evil Lens, which allows her to see through enemy illusions. She is voiced by Satomi Akesaka in the anime.